Abstract

A diagnosis of cervical cancer during pregnancy often requires difficult management decisions. This review focuses on the current literature and practice with regards to diagnosis and management. We explore the role of surgery, chemoradiation and neo-adjuvant chemotherapy. Treatment decisions are influenced by the stage of the cancer, the histological type, the stage of the pregnancy and the patients wishes. Both maternal and fetal safety and wellbeing has to be taken into account. Termination of pregnancy is not indicated in all cases. Pregnancy preservation in tumours diagnosed during early gestation is feasible in carefully selected cases. Discussion with the patient and her family is essential and treatment has to be individualised.

Keywords: Cervical cancer, pregnancy, chemoradiation, neo-adjuvant chemotherapy, trachelectomy