Abstract

Silica sulfuric acid (SSA) has been used as an efficient solid acidic catalyst for many organic reactions. In this review, we wish to report some applications of this catalyst in organic synthesis.

Keywords: Silica sulfuric acid (SSA), heterogeneous catalyst, organic reactions, hexamethyldisilazane, HMDS, Fischer glycosylation, Alzheimer's disease, Angiotensin II, benzyloxycarbonyl, N-benzyloxycarbonylation, sequential diazotization, Methoxymethylation, Beckmann rearrangement, Friedel-Crafts Alkylation, Zolpidem, Alpidem, microwave irradiation, vasorelaxant, Hantzsch four-component condensation reaction, Pechmann Reaction