Abstract

Enantioselective ring-opening reaction of meso-epoxides with arylselenols using a chiral (salen)Ti(IV) complex as catalyst was realized, and 1,2- arylseleno alcohols were obtained in good yields and up to 80 % ee.

Keywords: Arylselenols, epoxides, ring-opening reaction, asymmetric catalysis, RNH2, ROH, TMSCN, RN3, RSH, mercaptoalcohols, Grignard reagents, scandium-bipyridine complex, selenophenol, Kozlowski's modular bifunctional salen ligands, Ring-Opening Reactiona, Schlenk techniques, NMR, Bruker AMX-300 spectrometer, mass spectrometer, chiral Chiralcel OD-H column, 2-(phenylseleno)-1-cyclohexanol, HPLC, 2-(phenylseleno)-1-cyclopentanol, 3-(phenylseleno)-2-butylol, 2-(naphthylseleno)-1-cyclohexanol