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Letters in Organic Chemistry

Author(s): Michalis Batistatos, Manolis A. Fousteris, Sotiris S. Nikolaropoulos, Jean Le Bras and Jacques Muzart

DOI: 10.2174/157017810791824829

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Selective 5-exo-trig Iodocyclization of N-tosyl-2-allylanilines in Water

Page: [440 - 443] Pages: 4

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Abstract

Various 2-iodomethyl-N-tosylindolines are obtained in high yields from the reaction of N-tosyl-2-allylanilines with iodine in water at 50°C.

Keywords: Iodocyclization, indolines, iodine, water