Mini-Reviews in Medicinal Chemistry

Author(s): G. Latini, G. Knipp, A. Mantovani, M.L. Marcovecchio, F. Chiarelli and O. Soder

DOI: 10.2174/138955710791608271

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Endocrine Disruptors and Human Health

Page: [846 - 855] Pages: 10

  • * (Excluding Mailing and Handling)

Abstract

Endocrine-disrupting chemicals (EDCs) are a group of diversely natural compounds or synthetic chemicals that can interfere with the programming of normal endocrine-signalling pathways during pre- and neonatal life, thus leading to adverse consequences later in life. In addition, early life exposure to EDCs may alter gene expression and consequently transmit these effects to future generations.

Keywords: Endocrine-disruptors, environment, endocrine system, phthalates, pregnancy, neonate, fetal