Mini-Reviews in Medicinal Chemistry

Author(s): G. Ferro-Flores, F. de M. Ramirez, L. Melendez-Alafort and C. L. Santos-Cuevas

DOI: 10.2174/138955710791112596

Peptides for In Vivo Target-Specific Cancer Imaging

Page: [87 - 97] Pages: 11

  • * (Excluding Mailing and Handling)

Abstract

Molecular imaging comprises non-invasive monitoring of functional and spatiotemporal processes at molecular and cellular levels in living systems. Advanced imaging techniques can monitor such processes. Peptide receptors over-expressed in tumours can be targeted by peptides conjugated to radionuclides, near-infrared fluorochromes, metallic nanoparticles or quantum dots for target-specific cancer imaging.

Keywords: Peptides, molecular imaging, quantum-dots, nanoparticles