Abstract

Over the last several years the need to improve efficiency and minimize waste has spurred chemists to develop new catalysts for a wider range of reactions that was previously only achievable using stoichiometric reagents. A very powerful approach at achieving this goal is through the use of multiple transition metal catalysed one-pot processes, whereby the desired target compound is synthesised in a single work-up step. In this review we highlight some of the most significant developments in this field that have occurred over the last 10 years.

Keywords: Multiple catalysis, tandem catalysis, metathesis, cross-coupling, metal-mediated cyclisation, addition, siteisolation