Author(s): Nathalie Ayerbe, Sylvain Routier, Isabelle Gillaizeau, Sebastien Tardy and Gerard Coudert
Page: [121 - 126] Pages: 6
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New series of structure based on original benzodioxine and benzoxazine heterocycles were prepared leading to potential anticancer lead compounds. In this paper, we described a convenient approach via a Diels-Alder cycloaddition in order to efficiently provide three new indole isosteres in indolocarbazoles series. Their first cytotoxic evaluation was also reported.
Keywords: Benzodioxine, benzoxazine, indolocarbazole, cytotoxicity
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