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Letters in Organic Chemistry

Author(s): Yan Zhang, Man Gang Wang, Jun Liang and Zhi Cai Shang

DOI: 10.2174/157017810790533995

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An Environment-Friendly and Efficient Method for Aldol Condensation Catalyzed by L-Lysine in Pure Water

Page: [27 - 31] Pages: 5

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Abstract

This is a new example of a nonmetallic small-molecule catalyst for direct intermolecular aldol reactions. We found L-lysine is an effective catalyst for this condensation between unmodified acetone and a variety of aldehydes in the presence of pure water. This green catalyst system could be reused.

Keywords: L-lysine, organo-catalysis, aldol reaction, green chemistry