Mini-Reviews in Medicinal Chemistry

Author(s): S. P. Chapela, N. Kriguer, E. H. Fernandez and C. A. Stella

DOI: 10.2174/138955709790361502

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Involvement of L-Carnitine in Cellular Metabolism: Beyond Acyl-CoA Transport

Page: [1518 - 1526] Pages: 9

  • * (Excluding Mailing and Handling)

Abstract

Carnitine is well-known for its role in the transport of fatty acids to the mitochondrial matrix, where β- oxidation takes place. This work describes novel functions for this compound and novel data on its pharmacokinetics.

Keywords: Carnitine, acetyl-L-carnitine, free radicals, apoptosis, acetylation