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Mini-Reviews in Medicinal Chemistry

Author(s): Amr Amin and Michael A. Buratovich

DOI: 10.2174/138955709790361566

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New Platinum and Ruthenium Complexes - the Latest Class of Potential Chemotherapeutic Drugs - a Review of Recent Developments in the Field

Page: [1489 - 1503] Pages: 15

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Abstract

New Platinum and Ruthenium complexes display antitumour and antimetastatic potentials and lower host toxicities. This mini-review examines some the more recent developments in this field, and explores their interactions with biologically-relevant species. The article also refers to more recent work in the area of molybdenum and copper(II) chemistry.

Keywords: Cisplatin, BBR3464, picoplatin, satraplatin, lipoplatin, NAMI-A, KP1019, RAPTA, cancer, chemotherapeutics