Abstract

This review highlights the development of new receptors based on enantiopure trans-cyclohexane-1,2-diamine, a chiral building block presenting unique structural and conformational properties. Different architectures sharing this structural motif, which were prepared following several synthetic approaches, have been summarized from the recent literature.

Keywords: Trans-cyclohexane-1, 2-diamine, chiral receptor, nitrogen, molecular recognition, macrocycles