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Letters in Organic Chemistry

Author(s): Wen-Wen Xu, Min Lin, Yang Huang, Li Chen and Zhuang-Ping Zhan

DOI: 10.2174/157017809790442970

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Iron Trichloride Catalyzed One-Pot Synthesis of Substituted Oxazoles from Propargylic Acetates and Amides under Microwave Irradiation

Page: [664 - 668] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

A rapid and efficient procedure under microwave irradiation, using silica gel-supported reagents for the synthesis of substitued oxazoles has been developed through iron trichloride catalyzed propargylation/cycloisomerization tandem reaction of propargylic acetates and amides.

Keywords: Iron trichloride, oxazole, microwave irradiation