Letters in Organic Chemistry

Author(s): Akshay M. Pansuriya, Mahesh M. Savant, Chirag V. Bhuva, Naval Kapuriya, Jyoti Singh and Yogesh T. Naliapara

DOI: 10.2174/157017809790442925

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Cation Exchange Resin (Indion 130): An Efficient, Environment Friendly and Recyclable Heterogeneous Catalyst for the Biginelli Condensation

Page: [619 - 623] Pages: 5

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Abstract

Ion exchange resin catalyzed multicomponent Biginelli reaction is studied for the synthesis of 3,4- dihydropyrimidin-2-ones. Among the various solid acid catalysts Indion-130 was found to be most efficient, recyclable and environmentally benign heterogeneous catalyst regarding reaction time, yield and ease of work up procedure.

Keywords: Biginelli reaction, 3,4-dihydropyrimidin-2-ones, Ion exchange resin, heterogeneous catalyst, Indion-130