Mini-Reviews in Medicinal Chemistry

Author(s): Meenakshi Dhanawat, Nirupam Das, Ramesh C. Nagarwal and S. K. Shrivastava

DOI: 10.2174/138955709789957323

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Antimalarial Drug Development: Past to Present Scenario

Page: [1447 - 1469] Pages: 23

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Abstract

Malaria is a global health problem that needs attention of drug discovery scientists to investigate novel compounds with high drug efficacy, safety and low cost to counter the malaria parasites that are resistant to existing drug molecules. This is an overview of past to present status of antimalarial drugs including newly researched candidates and also the alternative approaches for the complete control of malaria.

Keywords: Malaria, antimalarials, drug-resistance, combination therapy, vaccines