Mini-Reviews in Medicinal Chemistry

Author(s): Kanghui Yang, Hao Fang, Jianzhi Gong, Li Su and Wenfang Xu

DOI: 10.2174/138955709789878097

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An Overview of Highly Optically Pure Chloramphenicol Bases: Applications and Modifications

Page: [1329 - 1341] Pages: 13

  • * (Excluding Mailing and Handling)

Abstract

Chloramphenicol (CAP) is a widely used broad-spectrum antibiotic. As the precursor of CAP, chloramphenicol bases are stereochemically pure agents and could be used as resolution agents, chiral catalysts and so on. This review summarizes these applications and discusses the structural modifications of chloramphenicol bases.

Keywords: Applications, chloramphenicol bases, structural modifications