Letters in Organic Chemistry

Author(s): Bin Hu, Qing-Fa Zhou, Kai Tang and Song Xue

DOI: 10.2174/157017809789869438

Synthesis of Trisubstituted-4H-Pyrans via Unexpected Cycloaddition of Aldehydes with Acetylenic Ketones Mediated by DMAP and 2,4- Pentanedione

Page: [560 - 563] Pages: 4

  • * (Excluding Mailing and Handling)

Abstract

A cycloaddition of aldehydes and acetylenic ketones mediated by 4-dimethylaminopyridine and 2,4- pentanedione is reported. The method supplies a facile way to synthesize 3,4,5-trisubstituted-4H-pyrans in moderate to good yields under mild conditions.

Keywords: Cycloaddition, acetylenic ketones, aldehydes, 4H-pyran, DMAP, 2,4-pentanedione