Letters in Organic Chemistry

Author(s): Yu Wan, Wei Lin, Xiu-Mei Chen, Yang Shen, Hai-Qiang Xin, Hua-Hong Xu, Rui Yuan, Li-Ling Pang, Rui Ma, Cai-Hui Yue, Wei Yin, Rong-Cheng Bo and Hui Wu

DOI: 10.2174/157017809789124920

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High Stereoselective Mannich Reaction Catalyzed by Starch Sulfonic Acid in Water

Page: [456 - 461] Pages: 6

  • * (Excluding Mailing and Handling)

Abstract

Starch sulfonic acid was used as efficient and highly stereoselective catalyst for the three-component Mannich reaction of aldehydes, amines, and ketones in water at ambient temperature to afford the corresponding β-amino ketones in good to excellent stereoselectivity and yields.

Keywords: Highly stereoselective, Mannich reaction, Starch sulfonic acid