Protein & Peptide Letters

Author(s): Hyeong H. Choe, Heejin Hwang, Seung Bum Kim, Sangyoung Yoon, Do Hyun Jo, Yeonwoo Ryu and T. Doohun Kim

DOI: 10.2174/092986609789055359

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Identification and Characterization of a Novel Oligomeric Decaprenyl Diphosphate Synthase

Page: [1036 - 1040] Pages: 5

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Abstract

A novel oligomeric decaprenyl pyrophosphate synthase was identified. Circular dichroism measurements indicated that it is alpha-helical, and stable against pH changes and denaturants. Three peptides corresponding to the conserved regions were synthesized and metal affinities were investigated. Crystallographic analyses of this oligomeric DDS are currently in progress.

Keywords: Decaprenyl diphosphate synthase, circular dichroism, metal affinities