Mini-Reviews in Medicinal Chemistry

Author(s): M. Reale, N. H. Greig and M. A. Kamal

DOI: 10.2174/138955709789055199

Peripheral Chemo-Cytokine Profiles in Alzheimers and Parkinsons Diseases

Page: [1229 - 1241] Pages: 13

  • * (Excluding Mailing and Handling)

Abstract

The identification of peripheral biomarkers for neurodegenerative diseases is required to improve the accuracy of clinical diagnosis and monitor both disease progression and response to treatments. The data reviewed in this paper suggest that, in neurodegenerative disease, cytokines are links between peripheral immune system and nervous system dysfunction.

Keywords: Alzheimer's Disease, Parkinson's Disease, neuroinflammation, neurodegeneration, cytokines, chemokines