Abstract

Pagets disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, deformity and other complications leading to significant disability and bone pain. Recently, the availability of newer, more potent nitrogen-containing bisphosphonates has improved treatment outcomes, allowing a more effective and convenient management of this disorder.

Keywords: Paget's disease of bone, bone turnover, bisphosphonates, zoledronic acid, pamidronate, neridronate