Protein & Peptide Letters

Author(s): Sandro G. Soares and Leandro L. Oliveira

DOI: 10.2174/092986609788923293

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Venom-Sweet-Venom: N-Linked Glycosylation in Snake Venom Toxins

Page: [913 - 919] Pages: 7

  • * (Excluding Mailing and Handling)

Abstract

Protein glycosylation represents one of the most important post-translational events, and is a mean of diversifying a protein without recourse to the genome. The venoms produced by snakes contain an abundance of glycoproteins with N-linked carbohydrates. N-linked glycosylation can ensure the correct folding of important functional domains. Characterization of carbohydrates structures aids in development of human therapeutics by snake venom toxins.

Keywords: N-linked oligosaccharides, snake venom, enzyme activity, serine protease