Letters in Organic Chemistry

Author(s): Li Wang, Ji Zhang, Na Wang, Xin-Bin Yang, Qin Wang and Xiao-Qi Yu

DOI: 10.2174/157017809788681419

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Asymmetric Catalysis of Diels-Alder Cycloaddition of 2-Alkenoyl Pyridine with Cyclopentadiene by Binaphthol-Titanium Complex

Page: [392 - 396] Pages: 5

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Abstract

Asymmetric Diels-Alder reactions between aza-chalcone and cyclopentadiene (CP) catalyzed by the binaphthol-titanium (BINOL – Ti) in the presence of HMPA (80 mole %) were studied. The products were obtained with up to 87% ees.

Keywords: Diels-Alder reaction, 2-alkenoyl pyridine, binaphthol-titanium complex, catalyst, aza-chalcone, cycloaddition