Author(s): Esmaeel Sharifi, Naghmeh Sattarahmady, Mehran Habibi-Rezaei, Mohammad Farhadi, Nader Sheibani, Faizan Ahmad and Ali Akbar Moosavi-Movahedi
Page: [653 - 659] Pages: 7
* (Excluding Mailing and Handling)
The effects of β-cyclodextrin (β-CyD) and trehalose on glycation of human serum albumin (HSA) were studied. These additives reduced AGEs and nanofibril formation of HSA under in vitro glycation conditions and improved its helical structure. These were accomplished through direct interactions of them with HSA and alterations in solute-protein interactions.
Keywords: Diabetes, trehalose, β-cyclodextrin, glycation, HSA, glucose
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