Author(s): Alessandro Pezzini, Elisabetta Del Zotto, Irene Volonghi, Alessia Giossi, Paolo Costa and Alessandro Padovani
Page: [794 - 804] Pages: 11
* (Excluding Mailing and Handling)
There is compelling evidence that treatment with 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors - “statins” - the most important class of lipid lowering agents, reduces ischemic stroke incidence independent on their effect on serum cholesterol levels. In this review, the non-lipid-mediated - “pleiotropic” - effects of statins as well as their potential implication in developing new treatment strategies for stroke prevention will be discussed.
Keywords: HMG-CoA reductase inhibitors, stroke, pleiotropic effects
Download PDF Flyer