Abstract

The reaction of 2-imino-3-(2-propynyl)-1,3-benzothiazole with various aryl iodides, catalyzed by Pd-Cu, in the presence of sodium lauryl sulfate as the surfactant and potassium carbonate as the base, in water, leads to the formation of 2-substituted imidazo[2,1-b][1,3]benzothiazoles.

Keywords: Sonogashira coupling, aryl iodide, imidazo[2,1-b][1,3]benzothiazole, Pd-catalyzed, potassium carbonate, sodium lauryl sulfate