Author(s): Kazushi Imai, Tadashige Chiba, Genta Maeda and Masako Morikawa
Page: [318 - 323] Pages: 6
* (Excluding Mailing and Handling)
Rheumatoid arthritis (RA) is a systematic inflammatory and intractable disease, which progressively affects multiple joints. Recent findings strongly suggest a key role of WNT signaling in the disease initiation and progression. In this review, we discuss the role and possibility of treatment by targeting WNT signaling.
Keywords: WNT, rheumatoid arthritis, FRP, β-catenin, synovium, matrix metalloproteinase
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