Mini-Reviews in Medicinal Chemistry

Author(s): R. A. Burgos, M. A. Hidalgo, C. D. Figueroa, I. Conejeros and J. L. Hancke

DOI: 10.2174/138955709787316092

DownloadDownload PDF Flyer Cite As
New Potential Targets to Modulate Neutrophil Function in Inflammation

Page: [153 - 168] Pages: 16

  • * (Excluding Mailing and Handling)

Abstract

The importance of neutrophils in human disease such as rheumatoid arthritis, asthma, adult respiratory distress syndrome, and COPD has prompted the search for drugs capable to slow down neutrophil-dependent inflammation, without interference with innate immune responses. In this review, we summarize new potential drugs targets against neutrophils mediated inflammatory responses.

Keywords: Neutrophil, drugs, innate immunity, inflammation