Abstract

The course of Kabachnik-Fields reaction in the synthesis of 3-substituted quinoline-based α-aminophosphonates under microwave irradiation has been investigated. Some unexpected monoester hydrogen phosphonate derivatives, obtained along with diethyl phosphonates by reaction of quinoline-3-carboxaldehyde and aniline as well as 3- aminoquinoline and benzaldehyde, respectively, with diethyl phosphite, have been analyzed and discussed.

Keywords: α-Aminophosphonate, quinoline, microwave-assisted reaction, Kabachnik-Fields reaction