Author(s): Ross P. McGeary, Andrew J. Bennett, Quoc B. Tran, Kelly L. Cosgrove and Benjamin P. Ross
Page: [1384 - 1394] Pages: 11
* (Excluding Mailing and Handling)
Suramin is a polysulfonated polyaromatic symmetrical urea. It is currently used to treat African river blindness and African sleeping sickness. Suramin has also been extensively trialed recently to treat a number of other diseases, including many cancers. Here, we examine its modes of action and discuss its structure-activity relationships.
Keywords: Suramin, trypanosomiasis, onchocerciasis, FGF
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