Abstract

This paper focuses on the latest developments in asymmetric epoxidation of electron-deficient olefins since the review by Porter and Skidmore on chiral ligand-metal peroxide systems, polyamino acid catalysed and organocatalysed epoxidations. Particular attention has been paid to the most recent advances using chiral pyrrolidines as organocatalysts.

Keywords: Asymmetric epoxidation, electron deficient olefins, organocatalysis, dioxiranes, chiral ligand, –, metal peroxide systems, Juliá Colonna epoxidation