Mini-Reviews in Medicinal Chemistry

Author(s): Emanuela Galliera, Massimiliano M. Corsi, Raffaella Bonecchi, Massimo Locati and Alberto Mantovani

DOI: 10.2174/138955708784567386

Chemokines as Pharmacological Targets

Page: [638 - 646] Pages: 9

  • * (Excluding Mailing and Handling)

Abstract

Chemokines play a key role in immune processes by controlling leukocyte recruitment in physiological and pathological condition. This review discusses the regulation of the chemokine system, its role in human diseases, and its potential relevance as a new pharmacological target.

Keywords: Chemokine, chemokine receptors, inflammation, GPCR inhibitors