Generic placeholder image

Mini-Reviews in Medicinal Chemistry

Author(s): S. Bastianetto, S. Krantic and R. Quirion

DOI: 10.2174/138955708784223512

DownloadDownload PDF Flyer Cite As
Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease

Page: [429 - 435] Pages: 7

  • * (Excluding Mailing and Handling)

Explore Articles
About Journal
For Authors
For Editors
For Reviewers

Abstract

Beta-amyloid (Aβ) likely plays a pivotal role in the etiology of Alzheimers disease (AD). Consequently, Aβ-associated pathways are targets for the development of possible effective AD therapies. This review first updates strategies aimed at the inhibition of Aβ formation and then discusses the role of food-derived polyphenols as putative antiamyloid drugs.

Keywords: Alzheimer's disease, polyphenols, neuroprotection