Letters in Organic Chemistry

Author(s): Pintu Kumar Mandal and Anup Kumar Misra

DOI: 10.2174/157017808783955880

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Efficient Acetylation and Boc Protection of Carbohydrates, Phenols and Amines

Page: [194 - 201] Pages: 8

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Abstract

An efficient acetylation and tert-butoxycarbonylation (Boc) of carbohydrate derivatives, phenols and amines catalyzed by tetrabutylammonium bromide is reported. The reaction condition is applicable to substrates containing acid and base labile functional groups. In most of the cases yields obtained were excellent.

Keywords: Carbohydrates, acetylation, tert-butoxycarbonyl, protecting groups, amines, phenols