Letters in Organic Chemistry

Author(s): Min Ji, Hai-Feng Liu, Xiao-Qing Wu, Yan-Bing Duan and Bin Gu

DOI: 10.2174/157017808783743920

An Efficient One-Pot, Two-Step Synthesis of Cyclobuxophyllinine M from Cyclovirobuxine D in Aqueous Media

Page: [140 - 141] Pages: 2

  • * (Excluding Mailing and Handling)

Abstract

A highly efficient one-pot, two-step sequential process consisting of modified Jones oxidation of aqueous cyclovirobuxine D acetate followed by Ruschig degradation after pH regulation with saturated aqueous NaOH, provided cyclobuxophyllinine M in high yield and in a single geometrical isomeric form.

Keywords: Jones oxidation, Ruschig degradation, cyclobuxophyllinine M, cyclovirobuxine D, aqueous media