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Letters in Organic Chemistry

Author(s): Javid H. Zaidi, Khalid M. Khan, Sadullah Mir, Naseem Iqbal Gunjial and M. Arfan

DOI: 10.2174/157017808783743894

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In Situ Synthesis of Benzyl Chloromethyl Ether and its Use for the Protection and Deprotection of Bifunctional Hydroxyl Compounds

Page: [125 - 127] Pages: 3

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Abstract

In situ synthesis of benzyl chloromethyl ether and its use to protect bifunctional hydroxyl compounds as benzyloxymethyl ethers is reported. This methodology was extended to alkylate the N-protected L-amino acids.

Keywords: Benzyl chloromethyl ether, protection, deprotection