Mini-Reviews in Medicinal Chemistry

Author(s): Fernando J. Corrales, Enrique Santamaria, Javier Munoz, Joaquin Fernandez-Irigoyen, Laura Sesma and Leticia Odriozola

DOI: 10.2174/138955708783331595

Proteomic Analysis of Liver Diseases: Molecular Mechanisms and Biomarker Discovery

Page: [1 - 9] Pages: 9

  • * (Excluding Mailing and Handling)

Abstract

Liver diseases afflict more than 10% of the world population. Although the main risk factors are known and the population at risk is monitored, new biomarkers are urgently needed to allow early diagnosis and hence more effective therapeutic interventions. Here, we revise the contribution of proteomics to the study of liver diseases and its potential impact in the clinical practice is evaluated.

Keywords: Proteomics, mass spectrometry, liver diseases, biomarkers