Letters in Organic Chemistry

Author(s): George B. Foscolos, Ioannis Papanastasiou and Andrew Tsotinis

DOI: 10.2174/157017808783330117

An Intriguing, Regioselective Synthesis of Novel 2-(1-Adamantylmethyl) tetrahydropyridines

Page: [57 - 59] Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

Treatment of piperidine 8 with acetyl chloride or ethyl chloroformate in the presence of triethylamine gave the 2,3-dehydrogenated products 10a and 10b, respectively, together with the expected N-acylpiperidines 9.

Keywords: N-acyl adamantylmethylpiperidines, N-acyl adamantylmethyltetrahydropiperidines, synthesis