A variety of bicyclo-heterocyclic compounds have been synthesized by ondensation of phthalic acid, homophathalic acid, 1,2-phenylenediacetic acid, 2,3-pyridine dicarboxlic acid, 3,4-pyridine dicarboxlic acid and 2,3-pyrazine dicarboxlic acid with 1-(2-aminoethyl)-piperidine and furfuryl amine, in one step using microwave irradiation technique. Bicyclo-heterocyclic compounds were obtained within minutes in good chemical yields and high purity.
Keywords: Microwave, bicyclo-heterocyclic, dicarboxlic acids, amines