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Letters in Organic Chemistry

Author(s): Robabeh Baharfar, Seyed M. Baghbanian, Roghayeh Hossein nia and Hamid R. Bijanzadeh

DOI: 10.2174/157017807782795547

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The Novel One-Pot Synthesis of Functionalized Vinyl Sulfides Using Triphenylphosphine Catalyzed Nucleophilic Addition of Thiols to Acetylenes

Page: [567 - 570] Pages: 4

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Abstract

3-mercapto-2-butanone undergoes a smooth reaction with electron-deficient symmetric and asymmetric acetylenes in the presence of catalytic amount of triphenylphosphine under neutral conditions to produce S-functionalized vinyl sulfides (Z/E isomers) in moderately high yields.

Keywords: Triphenylphosphine, alkyl propiolate, organophosphorus compounds, vinyl sulfides