Enantiospecific Synthesis of (-)-Radicamine B

Chunyan      Liu; Junchao      Gao; Guang      Yang; Richard   H.   Wightman; Shende      Jiang

Letters in Organic Chemistry

Author(s): Chunyan Liu, Junchao Gao, Guang Yang, Richard H. Wightman and Shende Jiang

DOI: 10.2174/157017807782795600

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Enantiospecific Synthesis of (-)-Radicamine B

Page: [556 - 558] Pages: 3

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Abstract

Radicamine B 2, the enantiomer of natural radicamine B 5, was synthesized via a chiral nitrone derived from D-xylose in 10 steps with an overall yield of 15%.

Keywords: Iminosugars, radicamine B, D-xylose, enantiospecific synthesis, nitrone

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