Abstract

Fluorine-containing molecules are now widely selected for both fundamental research and industrial applications in the fields of pharmaceuticals, agrochemicals, and advanced materials. The development of methodologies for the efficient synthesis of fluorine-containing molecules has become one of the most important issues in organic chemistry for long time. This mini-review focuses on the recent development in the one-pot syntheses of some important fluorinated building blocks which are recognized as the versatile tools for the construction of fluorine-containing molecules.

Keywords: One-pot synthesis, multi-component reaction, fluorinated building block, fluorinated heterocycles