Abstract

Temporin A is one of a group of 31 structurally similar antibiotic peptides isolated from the skins of anurans, 10 of which were isolated from the European red frog, Rana temporaria. The synthesis and bacteriological study of temporin A and 8 analogs were reported previously, and this article describes the synthesis and analyses of 11 new temporin A analogs, and a cecropin A-temporin A hybrid peptide

Keywords: Temporin, Rana temporaria, Synthesis, new temporin A analogs, cecropin A-temporin A hybrid peptide, Candida albicans, albicans, Staphylococcus aureus, Enterococci, Escherichia coli