Abstract

The circular dichroism spectrum in the far UV-region (190-240 nm) indicates that the acid protease from Aspergillus saitoi contains appreciable amounts of beta-sheet. The structure-activity relationship of the protein is studied as a function of the pH.

Keywords: acid protease, aspergillus saitoi, pepsin, gastricsin, cathepsins d e, renin, pepsinlilke acid proteases