Mini-Reviews in Medicinal Chemistry

Author(s): R. Baranowski and K. pacha

DOI: 10.2174/1389557024605465

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Gas Chromatographic Determination of Prostaglandins

Page: [135 - 144] Pages: 10

  • * (Excluding Mailing and Handling)

Abstract

Progress in separation and detection of prostaglandins and the other metabolites of arachidonic acid by means of GC-ECD, GC-MS, and GC-MS-MS in the course of the past fifteen years was reviewed. One discussed the problems of sample preparation, selection of proper chromatographic conditions, and detection modes available. Finally, applications of the methods developed to detection and quantification of prostanoids in biological material was presented.

Keywords: Gas Chromatographic