Mini-Reviews in Medicinal Chemistry

Author(s): Patricia Benoit and Jean-Michel Dogné

DOI: 10.2174/1389557033405412

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Platelet ADP Receptors and their Antagonists

Page: [145 - 148] Pages: 4

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Abstract

ADP plays a crucial role in haemostasis and thrombosis and its receptors are potential target for antithrombotic drugs.The knowledge of the ADP-receptors has been amplified by recent discoveries. This review highlights the ADP-receptors models and their antagonists described in the recent literature, mainly the thienopyridine derivatives.

Keywords: adenosine diphosphate, adp receptors, receptors, antithrombotics, platelets