Mini-Reviews in Medicinal Chemistry

Author(s): Hernan Pessoa-Mahana, Ramiro Araya-Maturana, B. Claudio Saitz and C. David Pessoa-Mahana

DOI: 10.2174/1389557033405278

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A Synthetic Overview of New Molecules with 5-HT1A Binding Affinities

Page: [77 - 93] Pages: 17

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Abstract

The present review discusses the synthetic strategies of new ligands exhibiting mainly 5-HT1A binding affinities. Specifically we focused our attention in the synthesis of compounds structurally related to arylpiperazine, 2-aminotetralin, and benzopyran derivatives.

Keywords: ligands, arylpiperazines, aminotetralins, benzopyrans