Author(s): Kazunobu Toshima, Yoko Nakajima, Yutaka Maeda and Shuichi Matsumura
Page: [31 - 33] Pages: 3
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Novel anthraquinone-carbohydrate hybrids were designed and synthesized as artificial DNA photocleavers. They were found to show high DNA cleaving activity under irradiation with a long wavelength UV light without any additives and also exhibited selective cytotoxicity against HeLa S3 cancer cells with the photoirradiation.
Keywords: anthraquinone, carbohydrate, photoirradiation, dna cleavage, cancer cells, cytotoxicity
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