Letters in Organic Chemistry

Author(s): A. Gilbert Cook, Karen A. Switek, Kenneth A. Cutler and Allison M. Witt

DOI: 10.2174/1570178043488734

Synthesis and Isomerization of 3-Pyrroline Enamines

Page: [1 - 5] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

3-Pyrroline reacts with cyclic ketones to form enamines as kinetically controlled products. Under more vigorous conditions, pyrroles are formed as thermodynamically controlled products by way of a 1,3- hydride shift.

Keywords: enamine, pyrrole, isomerization, pyrroline