Abstract

Changing substituents on phosphorus ligands can cause marked changes in the behaviour of the free ligands and of their transition metal complexes. In this review, we will describe the synthesis and the application of P(t-Bu)3, an efficient ligand in numerous homogeneous catalytic systems and rationalise its singular behaviour.

Keywords: tri-tert-butyl phosphine (p(t-bu)3), palladium, catalysis, amination, cross coupling